RESUMO
Seroprevalence of HHV-8 has been studied in Malaysia, India, Sri Lanka, Thailand, Trinidad, Jamaica and the USA, in both healthy individuals and those infected with HIV. Seroprevalence was found to be low in these countries in both the healthy and the HIV-infected populations. This correlates with the fact that hardly any AIDS-related Kaposi's sarcoma has been reported in these countries. In contrast, the African countries of Ghana, Uganda and Zambia showed high seroprevalences in both healthy and HIV-infected populations. This suggests that human herpes virus-8 (HHV-8) may be either a recently introduced virus or one that has extremely low infectivity. Nasopharyngeal and oral carcinoma patients from Malaysia, Hong Kong and Sri Lanka who have very high EBV titres show that only 3/82 (3.7%) have antibody to HHV-8, demonstrating that there is little, if any, cross-reactivity between antibodies to these two gamma viruses.
Assuntos
Infecções por Herpesviridae/epidemiologia , Herpesvirus Humano 8/imunologia , Sarcoma de Kaposi/epidemiologia , Adolescente , Adulto , África/epidemiologia , Idoso , Idoso de 80 Anos ou mais , Linfoma de Burkitt/epidemiologia , Região do Caribe/epidemiologia , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Nasofaríngeas/epidemiologia , Estudos Soroepidemiológicos , Estados Unidos/epidemiologiaRESUMO
Seroprevalence of HHV-8 has been studied in Malaysia, India, Sri Lanka, Thailand, Trinidad, Jamaica and the USA, in both healthy individuals and those infected with HIV. Seroprevalence was found to be low in these countries. In contrast, the African countries of Ghana, Uganda and Zambia showed high seroprevalences in both healthy and HIV-infected populations. This suggests that human herpes virus-8 (HHV-8) may be either a recently introduced virus or one that has extremely low infectivity. Nasopharyngeal and oral carcinoma patients from Malaysia, Hong Kong and Sri Lanka who have very high EBV titres to show that only 3/82 (3.7 percent) have antibody to HHV-8, demonstrating that there is little, if any, cross-relativity between antibodies to these two gamma viruses. (AU)
Assuntos
Adulto , Idoso , Humanos , Masculino , Feminino , Adolescente , Estudo Comparativo , Criança , Pessoa de Meia-Idade , Infecções por Herpesviridae/epidemiologia , Herpesvirus Humano 8/imunologia , Sarcoma de Kaposi/epidemiologia , África/epidemiologia , Idoso de 80 Anos ou mais , Linfoma de Burkitt/epidemiologia , Região do Caribe/epidemiologia , Neoplasias Nasofaríngeas/epidemiologia , Estudos Soroepidemiológicos , Estados Unidos/epidemiologiaRESUMO
Egg surface antigens of Setaria digitata were investigated by an immunoperoxidase staining technique. Certain antigens on the egg surface were shed when the eggs developed to microfilariae. Rabbit antisera to S. digitata eggs and to the soluble egg antigen reacted (as detected by immunoperoxidase staining) with the surface antigens of S. digitata eggs and immature microfilariae, and with mature microfilariae of Wuchereria bancrofti and Dirofilaria repens, but not with the surface antigens of mature microfilariae of S. digitata.
